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Anti-Xanthine Oxidase/XDH Antibody Picoband® Europäischer Partner

ArtNr BOS-A01884
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, FC, IHC, ICC, IHC-F
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations 1. Ichida K, Amaya Y, Noda K, Minoshima S, Hosoya T, Sakai O, Shimizu N, Nishino T (Nov 1993). "Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene". Gene. 133 (2): 279–84.
2. Parzen SD, Fox AS (Dec 1964). "Purification of xanthine dehydrogenase from drosophila melanogaster". BiochimicaetBiophysicaActa. 92: 465–71.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Xanthine dehydrogenase/oxidase;Xanthine dehydrogenase;XD;1.17.1.4 ;Xanthine oxidase;XO;1.17.3.2 ;Xanthine oxidoreductase;XOR;XDH;XDHA;
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
146 kDa
Calculated Molecular weight
146424 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Mouse, Rat, Human

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Mouse, Rat, Human, By Heat

Immunohistochemistry (Frozen Section), 0.5-1?g/ml, Human

Immunocytochemistry, 0.5-1?g/ml, Human

Flow Cytometry (Fixed), 1-3?g/1x106 cells, Human
Manufacturer - Gene Name
XDH
Gene Full Name
Xanthine dehydrogenase/oxidase
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene. Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Immunogen
E. coli-derived human Xanthine Oxidase recombinant protein (Position: T2-K343). Human Xanthine Oxidase shares 86.8% and 89.2% amino acid (aa) sequence identity with mouse and rat Xanthine Oxidase, respectively.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Function
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Subcellular Localization
Cytoplasm. Peroxisome. Secreted.
Description
Boster Bio Anti-Xanthine Oxidase/XDH Antibody Picoband® catalog # A01884. Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Detected in milk (at protein level).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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