Anti-UBE2I/UBC9 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

18007 MW

Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat

SUMO-conjugating enzyme UBC9

SUMO-conjugating enzyme UBC9 (UBE2I), also called UBC9,   is a  protein  that in humans is encoded by the  UBE2I  gene. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. It is mapped to 16p13.3. UBC9 could fully complement the mutant phenotype of a yeast ubc9 mutant strain. This gene may play a similar role via interaction with WT1, which is able to impose a block to cell cycle progression in eukaryotic cells. What's more, it could support the growth of yeast ubc9 temperature-sensitive mutants at nonpermissive temperatures, indicating that the gene is a functional homolog of yeast ubc9. UBC9 is specifically associated with FHIT, such as FHIT may be involved in cell cycle control through its interaction with  UBC9.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Cell Biology, 2339, Epigenetics and Nuclear Signaling, Metabolism, Obesity, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly- SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'.

Boster Bio Anti-UBE2I/UBC9 Antibody catalog # PA2258. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Belongs to the ubiquitin-conjugating enzyme family.