Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

25722 MW

Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat

Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Mouse, Rat

Immunofluorescence, 2?g/ml, Mouse, Rat

Gremlin-1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Cytokines, Cytoskeleton/ECM, Embryonic Stem Cells, Extracellular Matrix, Signal Transduction, Stem Cells, Structures

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Boster Bio Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody Picoband® catalog # PB9627. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Contains 1 HMG box DNA-binding domain.