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Anti-GAB1 Antibody Picoband®

Anti-GAB1 Antibody Picoband®

ArtNr	BOS-A01989-1
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Blastoma Western Blot Primary Antibodies By Organ Bladder Cancer
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Entrez Gene: GAB1 GRB2-associated binding protein 1. 2. Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ (April 1996). A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature. 379 (6565): 560–4. 3. Rocchi S, Tartare-Deckert S, Murdaca J, Holgado-Madruga M, Wong AJ, Van Obberghen E (July 1998). Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules. Mol. Endocrinol. 12 (7): 914–23.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GRB2-associated-binding protein 1,GRB2-associated binder 1,Growth factor receptor bound protein 2-associated protein 1,GAB1
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	77 kDa
Calculated Molecular weight	76616 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Gene Name	GAB1
Gene Full Name	GRB2-associated-binding protein 1
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. It is mapped to 4q31.21. The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human GAB1, different from the related mouse sequence by one amino acid.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Adapters, Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Cytoplasmic, Intracellular, Kinases, MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Name	GRB2-associated-binding protein 1
Protein Function	Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
Subcellular Localization	Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Description	Boster Bio Anti-GAB1 Antibody Picoband® catalog # A01989-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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BOS-A01989-1-datasheet.pdf

BOS-A01989-1-safety-datasheet.pdf