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Anti-ABP1/AOC1 Antibody Picoband® Europäischer Partner

ArtNr BOS-PB10040
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IF, IHC, ICC
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. “Human kidney amiloride-binding protein: cDNA structure and functional expression."Barbry P., Champe M., Chassande O., Munemitsu S., Champigny G., Lingueglia E., Maes P., Frelin C., Tartar A.,Ullrich A., Lazdunski M.Proc. Natl. Acad. Sci. U.S.A. 87:7347-7351(1990) .
2. "Structure and inhibition of human diamine oxidase."McGrath A.P., Hilmer K.M., Collyer C.A., Shepard E.M., Elmore B.O., Brown D.E., Dooley D.M., Guss J.M.Biochemistry 48:9810-9822(2009).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Amiloride-sensitive amine oxidase [copper-containing];DAO;Diamine oxidase;1.4.3.22 ;Amiloride-binding protein 1;Amine oxidase copper domain-containing protein 1;Histaminase;Kidney amine oxidase;KAO;AOC1;ABP1, DAO1;
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Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
85 kDa
Calculated Molecular weight
85378 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Monkey

Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Human

Flow Cytometry (Fixed), 1-3 ?g/1x106 cells, Human
Manufacturer - Gene Name
AOC1
Gene Full Name
Amiloride-sensitive amine oxidase [copper-containing]
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ABP1, different from the related mouse sequence by ten amino acids, and from the related rat sequence by eight amino acids.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cell Biology
Protein Name
Amiloride-sensitive amine oxidase [copper-containing]
Protein Function
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Subcellular Localization
Secreted, extracellular space.
Description
Boster Bio Anti-ABP1/AOC1 Antibody Picoband® catalog # PB10040. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Placenta and kidney.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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