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Anti-Decorin/DCN Antibody Picoband® Europäischer Partner

ArtNr BOS-PB9174
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <5pg/ml
Citations 1. Danielson, K. G.; Fazzio, A.; Cohen, I.; Cannizzaro, L. A.; Eichstetter, I.; Iozzo, R. V. : The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5-prime untranslated region, and mapping of the gene to chromosome 12q23. Genomics 15: 146-160, 1993.
2. Vetter, U.; Vogel, W.; Just, W.; Young, M. F.; Fisher, L. W. : Human decorin gene: intron-exon junctions and chromosomal localization. Genomics 15: 161-168, 1993.
3. Scholzen, T.; Solursh, M.; Suzuki, S.; Reiter, R.; Morgan, J. L.; Buchberg, A. M.; Siracusa, L. D.; Iozzo, R. V. : The murine decorin: complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J. Biol. Chem. 269: 28270-28281, 1994.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Decorin;Bone proteoglycan II;PG-S2;PG40;DCN;SLRR1B;
Similar products Bone proteoglycan II antibody, CSCD antibody, DCN antibody, DCN protein antibody, Decorin antibody, Decorin proteoglycan antibody, Dermatan sulphate proteoglycans II antibody, DKFZp686J19238 antibody, DSPG 2 antibody, DSPG2 antibody, PG 40 antibody, PG II antibody, PG S2 antibody, PG-S2 antibody, PG40 antibody, PGII antibody, PGS 2 antibody, PGS2 antibody, PGS2_HUMAN antibody, Proteoglycan core protein antibody, SLRR1B antibody, Small leucine rich protein 1B antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
40-50 kDa, 80-140 kDa.
Calculated Molecular weight
39747 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat
Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat
Manufacturer - Gene Name
DCN
Gene Full Name
Decorin
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Decorin is a protein that in humans is encoded by the DCN gene. This gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines.
Immunogen
E.coli-derived human Decorin recombinant protein (Position: D31-K359). Human Decorin shares 80% and 77% amino acid (aa) sequences identity with mouse and rat Decorin, respectively.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Collagen, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Growth Factors/Hormones, Signal Transduction, Structures
Protein Name
Decorin
Protein Function
May affect the rate of fibrils formation.
Subcellular Localization
Secreted, extracellular space, extracellular matrix.
Description
Boster Bio Anti-Decorin/DCN Antibody Picoband® catalog # PB9174. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed at low levels in the lung, kidney and spleen.
Sequence Similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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