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Anti-PTOV1 Antibody

Anti-PTOV1 Antibody

Hersteller	Boster
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Specific against	Human, Rat
Isotype	IgG
Format	Lyophilized
Applikationen	WB
Menge	100 ug/vial
Host	Rabbit
ArtNr	BOS-RP1087
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Cancer, Cell Cycle, Cell Division, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors, Tumor Antigens, Tumor Biomarkers
Short Description	Boster Bio Anti-PTOV1 Antibody catalog # RP1087. Tested in WB applications. This antibody reacts with Human, Rat.
Description	Boster Bio Anti-PTOV1 Antibody catalog # RP1087. Tested in WB applications. This antibody reacts with Human, Rat.
Background	Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.
Gene Name	PTOV1
Application Details	Western blot, 0.1-0.5μg/ml, Rat, Human
Application Notes	Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Predicted Reactivity	Hamster
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1, different from the related mouse and rat sequences by one amino acid.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	Prostate tumor-overexpressed gene 1 protein
Molecular Weight	46869 MW
Protein Function	May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation..
Subcellular Localization	Cell membrane. Cytoplasm, perinuclear region. Nucleus. Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts.
Tissue Specificity	Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine..
Protein Name	Prostate tumor-overexpressed gene 1 protein
Sequence Similarities	Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.

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