Manufacturer |
Boster
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Rat |
Isotype |
IgG |
Format |
Lyophilized |
Applications |
WB |
Amount |
100 ug/vial |
Host |
Rabbit |
Item no. |
BOS-RP1087 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Cancer, Cell Cycle, Cell Division, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors, Tumor Antigens, Tumor Biomarkers |
Short Description |
Boster Bio Anti-PTOV1 Antibody catalog # RP1087. Tested in WB applications. This antibody reacts with Human, Rat. |
Description |
Boster Bio Anti-PTOV1 Antibody catalog # RP1087. Tested in WB applications. This antibody reacts with Human, Rat. |
Background |
Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. |
Gene Name |
PTOV1 |
Application Details |
Western blot, 0.1-0.5μg/ml, Rat, Human |
Application Notes |
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Predicted Reactivity |
Hamster |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1, different from the related mouse and rat sequences by one amino acid. |
Purification |
Immunogen affinity purified. |
Cross-reactivity |
No cross-reactivity with other proteins |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
Prostate tumor-overexpressed gene 1 protein |
Molecular Weight |
46869 MW |
Protein Function |
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.. |
Subcellular Localization |
Cell membrane. Cytoplasm, perinuclear region. Nucleus. Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. |
Tissue Specificity |
Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.. |
Protein Name |
Prostate tumor-overexpressed gene 1 protein |
Sequence Similarities |
Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.