ArtNr |
BOS-A00470-Biotin |
Hersteller |
Boster
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized |
Applikationen |
ELISA |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Biotin |
Citations |
Das, K., Lin, Y., Widen, E., Zhang, Y., Scherer, P. E. Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem. Biophys. Res. Commun. 280: 1120-1129, 2001. Schaffler, A., Orso, E., Palitzsch, K.-D., Buchler, C., Drobnik, W., Furst, A., Scholmerich, J., Schmitz, G. The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH). Biochem. Biophys. Res. Commun. 260: 416-425, 1999. |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Galectin-1; Gal-1; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1; Lgals1; Gbp; |
Lieferbar |
|
Specificity |
No cross reactivity with other proteins. |
Manufacturer - Category |
Primary Antibodies |
Storage Conditions |
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
15 kDa |
Calculated Molecular weight |
33477 MW |
Clonality |
Polyclonal |
Application Details |
Western blot, 0.1-0.5?g/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml ELISA (Cap), 1-5?g/ml |
Manufacturer - Gene Name |
Lgals1 |
Gene Full Name |
galectin 1 |
Manufacturer - Specificity |
No cross reactivity with other proteins. |
Background |
Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process. |
Immunogen |
E. coli-derived mouse Galectin 1 recombinant protein (Position: A2-E135). |
Contents |
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml. |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml. |
Manufacturer - Research Category |
Cell Biology |
Protein Name |
Tumor necrosis factor ligand superfamily member 10 |
Protein Function |
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. |
Description |
Boster Bio Anti-Galectin 1/Lgals1 Antibody Picoband® catalog # A00470. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Tissue Specificity |
Widespread; most predominant in spleen, lung and prostate. |
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