Manufacturer |
Boster
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Mouse |
Isotype |
IgG |
Format |
Lyophilized |
Applications |
ELISA |
Amount |
100 ug/vial |
Host |
Rabbit |
Item no. |
BOS-A00470-Biotin |
Conjugate/Tag |
Biotin |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Cell Biology |
Short Description |
Boster Bio Anti-Galectin 1 Biotinylated Lgals1 Antibody catalog # A00470-Biotin. Tested in ELISA applications. This antibody reacts with Mouse. |
Description |
Boster Bio Anti-Galectin 1 Biotinylated Lgals1 Antibody catalog # A00470-Biotin. Tested in ELISA applications. This antibody reacts with Mouse. |
Background |
Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process. |
Gene Name |
LGALS1 |
Application Details |
ELISA Detection (Matched Antibody Pair), 0.1-0.5μg/ml |
Application Notes |
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
E. coli-derived mouse Galectin 1 recombinant protein (Position: A2-E135). |
Purification |
Immunogen affinity purified. |
Cross-reactivity |
No cross-reactivity with other proteins. |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
lectin, galactose binding, soluble 1 |
Protein Function |
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. |
Subcellular Localization |
Secreted, extracellular space, extracellular matrix |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.