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Anti-Hsp27/Hspb1 Antibody Picoband™

Anti-Hsp27/Hspb1 Antibody Picoband™

Hersteller	Boster
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody Primary
Specific against	Mouse, Rat
Isotype	IgG
Format	Lyophilized
Applikationen	WB, IHC, ELISA
Menge	100 ug/vial
Host	Rabbit
ArtNr	BOS-A00676
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Atherosclerosis, Cancer, Cardiovascular, Chaperones, Contractility, Heat Shock Proteins, Protein Trafficking, Signal Transduction, Tumor Biomarkers
Short Description	Boster Bio Anti-Hsp27/Hspb1 Antibody Picoband™ catalog # A00676. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
Description	Boster Bio Anti-Hsp27/Hspb1 Antibody Picoband™ catalog # A00676. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
Background	HSPB1 (Heat shock 27kDa protein 1), also known as HSP27, is a protein that in humans is encoded by the HSPB1 gene. It is mapped to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
Gene Name	HSPB1
Application Details	Western blot, 0.1-0.5μg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml Direct ELISA, 0.1-0.5μg/ml
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	E. coli-derived mouse Hsp27 recombinant protein (Position: M1-K209).
Cross-reactivity	No cross-reactivity with other proteins.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	heat shock protein 1
Molecular Weight	27 kDa
Protein Function	Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization (PubMed:17661394). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (By similarity).
Subcellular Localization	Cytoplasm.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug/vial

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Lieferung vsl. bis 30.05.2024

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