Manufacturer |
Boster
|
Category |
|
Type |
Antibody Primary |
Specific against |
Mouse, Rat |
Isotype |
IgG |
Format |
Lyophilized |
Applications |
WB, IHC, ELISA |
Amount |
100 ug/vial |
Host |
Rabbit |
Item no. |
BOS-A00676 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Atherosclerosis, Cancer, Cardiovascular, Chaperones, Contractility, Heat Shock Proteins, Protein Trafficking, Signal Transduction, Tumor Biomarkers |
Short Description |
Boster Bio Anti-Hsp27/Hspb1 Antibody Picoband™ catalog # A00676. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. |
Description |
Boster Bio Anti-Hsp27/Hspb1 Antibody Picoband™ catalog # A00676. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. |
Background |
HSPB1 (Heat shock 27kDa protein 1), also known as HSP27, is a protein that in humans is encoded by the HSPB1 gene. It is mapped to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). |
Gene Name |
HSPB1 |
Application Details |
Western blot, 0.1-0.5μg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml Direct ELISA, 0.1-0.5μg/ml |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
E. coli-derived mouse Hsp27 recombinant protein (Position: M1-K209). |
Cross-reactivity |
No cross-reactivity with other proteins. |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
heat shock protein 1 |
Molecular Weight |
27 kDa |
Protein Function |
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization (PubMed:17661394). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (By similarity). |
Subcellular Localization |
Cytoplasm. |
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