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Anti-PLCG1 (Ab-771) Antibody Europäischer Partner

ArtNr BOS-A00677
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;3.1.4.11;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1;PLCG1;PLC1;
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Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
148532 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name
PLCG1
Gene Full Name
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1
Background
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Denis Tvorogov, J. Cell Sci., Feb 2005; 118: 601 - 610.
Brenda J. Irvin, Mol. Cell. Biol., Dec 2000; 20: 9149 - 9161.
Benoit Poulin, J. Biol. Chem., Feb 2000; 275: 6411.
Ichiro Nakamura, J. Cell Biol., Jan 2001; 152: 361.
Immunogen
Synthesized non-phosphopeptide derived from human PLCG1 around the phosphorylation site of tyrosine 771 (P-D-Y-G-A).
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Lipid Metabolism, Lipid Signaling, Metabolism, Signal Transduction, Signaling Pathway
Protein Function
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Subcellular Localization
Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Short Description
Boster Bio Anti-PLCG1 (Ab-771) Antibody (Catalog # A00677). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-PLCG1 (Ab-771) Antibody (Catalog # A00677). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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