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Anti-Protein DBF4 homolog A DBF4 Antibody

Anti-Protein DBF4 homolog A DBF4 Antibody

ArtNr	BOS-A01348-1
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein DBF4 homolog A;Activator of S phase kinase;Chiffon homolog A;DBF4-type zinc finger-containing protein 1;DBF4;ASK, DBF4A, ZDBF1;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	76858 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	DBF4
Gene Full Name	Protein DBF4 homolog A
Background	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999). Jiang W., EMBO J. 18:5703-5713(1999). Ota T., Nat. Genet. 36:40-45(2004).
Immunogen	Synthesized peptide derived from N-terminal of human DBF4.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Cell Biology, Cell Cycle, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, Kinases/Phosphatases
Protein Function	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Subcellular Localization	Nucleus.
Short Description	Boster Bio Anti-Protein DBF4 homolog A DBF4 Antibody (Catalog # A01348-1). Tested in WB applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-Protein DBF4 homolog A DBF4 Antibody (Catalog # A01348-1). Tested in WB applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Highly expressed in testis and thymus. Expressed also in most cancer cells lines.

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BOS-A01348-1-datasheet.pdf

BOS-A01348-1-safety-datasheet.pdf