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Anti-SLCO1B1/Oatp2 Antibody

Anti-SLCO1B1/Oatp2 Antibody

ArtNr	BOS-A01375
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Hormones Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Solute carrier organic anion transporter family member 1B1;Liver-specific organic anion transporter 1;LST-1;OATP-C;Sodium-independent organic anion-transporting polypeptide 2;OATP-2;Solute carrier family 21 member 6;SLCO1B1;LST1, OATP1B1, OATP2, OATPC, SLC21A6;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	76449 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	SLCO1B1
Gene Full Name	Solute carrier organic anion transporter family member 1B1
Background	Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver. Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999). Keppler D., J. Biol. Chem. 275:23161-23168(2000). Venter J.C., Submitted (JUL-2005).
Immunogen	Synthesized peptide derived from internal of human SLCO1B1.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Cancer, Cancer Metabolism, Cell Type Markers, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Tags & Cell Markers
Protein Function	Mediates the Na (+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.
Subcellular Localization	Basolateral cell membrane; Multi-pass membrane protein. Detected in basolateral membranes of hepatocytes.
Short Description	Boster Bio Anti-SLCO1B1/Oatp2 Antibody (Catalog # A01375). Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-SLCO1B1/Oatp2 Antibody (Catalog # A01375). Tested in WB applications. This antibody reacts with Human.
Tissue Specificity	Highly expressed in liver, at the basolateral membranes of centrilobular hepatocytes. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.

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