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Anti-ACVL1 ACVRL1 Antibody Europäischer Partner

ArtNr BOS-A01468-1
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein kinase receptor R3;SKR3;2.7.11.30;Activin receptor-like kinase 1;ALK-1;TGF-B superfamily receptor type I;TSR-I;ACVRL1;ACVRLK1, ALK1;
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Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
56124 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name
ACVRL1
Gene Full Name
Serine/threonine-protein kinase receptor R3
Background
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
ten Dijke P., Oncogene 8:2879-2887(1993).
Attisano L., Cell 75:671-680(1993).
Berg J.N., Am. J. Hum. Genet. 61:60-67(1997).
Immunogen
Synthesized peptide derived from internal of human ACVL1.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Amino Acid Metabolism, Amino Acids, Angiogenesis, Cancer, Cardiovascular, Growth Factors, Growth Factors/Hormones, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Vasculature
Protein Function
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Subcellular Localization
Cell membrane; Single-pass type I membrane protein.
Short Description
Boster Bio Anti-ACVL1 ACVRL1 Antibody (Catalog # A01468-1). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-ACVL1 ACVRL1 Antibody (Catalog # A01468-1). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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