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Anti-LC3a MAP1LC3A Antibody

Anti-LC3a MAP1LC3A Antibody

ArtNr	BOS-A01543
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies Oligodendrocyte Markers Astroglia Markers
Typ	Antibody
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Microtubule-associated proteins 1A/1B light chain 3A;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B light chain 3 A;MAP1A/MAP1B LC3 A;Microtubule-associated protein 1 light chain 3 alpha;MAP1LC3A;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	14272 MW
Clonality	Polyclonal
Application Details	Predicted MW: 18 16 kd Western blotting: 1:500~1:1000 Immunofluorescence: 1:100~1:200
Manufacturer - Gene Name	MAP1LC3A
Gene Full Name	Microtubule-associated proteins 1A/1B light chain 3A
Background	Probably involved in formation of autophagosomal vacuoles (autophagosomes).
Immunogen	Peptide sequence around aa.5~10 (R-P-F-K-Q) derived from Human LC3A.
Contents	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration	1 mg/ml
Manufacturer - Research Category	Cancer, Cardiovascular, Cell Death, Cytoskeleton, Cytoskeleton/ECM, Metabolism, Metabolism Processes, Microtubules, Pathways and Processes, Signal Transduction
Protein Function	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600).
Subcellular Localization	Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. LC3-II binds to the autophagic membranes.
Short Description	Boster Bio Anti-LC3a MAP1LC3A Antibody (Catalog # A01543). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-LC3a MAP1LC3A Antibody (Catalog # A01543). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

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BOS-A01543-datasheet.pdf

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