Anti-Urocortin Antibody

UCN

No

Polyclonal antibody for Urocortin/UCN detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC. Reactive species: Human. Urocortin/UCN information: Molecular Weight: 13458 MW; Subcellular Localization: Secreted; Tissue Specificity: Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level). Expressed in pituitary and adrenal glands (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481).

A peptide derived from human Urocortin. Immunogen sequence location: 71-120

At -20° C for one year. After reconstitution, at 4° C for one month. It can also be aliquotted and stored frozen at -20° C for a longer time.Avoid repeated freezing and thawing.

Human, Mouse, Rat

Urocortin, UCN,

Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563). Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity). .