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Anti-Urocortin UCN Antibody

Anti-Urocortin UCN Antibody

Manufacturer	Boster
Category	Metabolism Glucose Homeostasis Regulation of Appetite Antibodies Obesity Immunohistochemistry Primary Antibodies
Type	Antibody
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Liquid
Applications	IF, ELISA, IHC-P
Amount	100ul
Host	Rabbit
Item no.	BOS-A01807-1
Targets	UCN
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies
Short Description	Boster Bio Anti-Urocortin UCN Antibody (Catalog# A01807-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Urocortin UCN Antibody (Catalog# A01807-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	UCN
Clonality	Polyclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application Details	Immunohistochemistry, 1:100 - 1:300 ELISA, 1:10000 Not yet tested in other applications.
Immunogen	A peptide derived from human Urocortin. Immunogen sequence location: 71-120
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Urocortin
Molecular Weight	13458 MW
Protein Function	Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563). Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity).
Subcellular Localization	Secreted.
Tissue Specificity	Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level). Expressed in pituitary and adrenal glands (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481).AS74

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 6/13/2024