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Anti-MEKKK 4 MAP4K4 Antibody

Anti-MEKKK 4 MAP4K4 Antibody

ArtNr	BOS-A02829
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Metabolism Diabetes Glucose Homeostasis Neural Signaling Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase kinase 4;2.7.11.1;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK 4;Nck-interacting kinase;MAP4K4;HGK, KIAA0687, NIK;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	142101 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name	MAP4K4
Gene Full Name	Mitogen-activated protein kinase kinase kinase kinase 4
Background	Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322. Yao Z., J. Biol. Chem. 274:2118-2125(1999). Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003). Ishikawa K., DNA Res. 5:169-176(1998).
Immunogen	Synthesized peptide derived from internal of human MEKKK 4.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Function	Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Subcellular Localization	Cytoplasm.
Short Description	Boster Bio Anti-MEKKK 4 MAP4K4 Antibody (Catalog # A02829). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-MEKKK 4 MAP4K4 Antibody (Catalog # A02829). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A02829-datasheet.pdf

BOS-A02829-safety-datasheet.pdf