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Anti-MEKKK 4 MAP4K4 Antibody

Anti-MEKKK 4 MAP4K4 Antibody

Item no.	BOS-A02829
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Neural Signaling Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase kinase 4;2.7.11.1;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK 4;Nck-interacting kinase;MAP4K4;HGK, KIAA0687, NIK;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	142101 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name	MAP4K4
Gene Full Name	Mitogen-activated protein kinase kinase kinase kinase 4
Background	Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322. Yao Z., J. Biol. Chem. 274:2118-2125(1999). Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003). Ishikawa K., DNA Res. 5:169-176(1998).
Immunogen	Synthesized peptide derived from internal of human MEKKK 4.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Function	Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Subcellular Localization	Cytoplasm.
Short Description	Boster Bio Anti-MEKKK 4 MAP4K4 Antibody (Catalog # A02829). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-MEKKK 4 MAP4K4 Antibody (Catalog # A02829). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A02829-datasheet.pdf

BOS-A02829-safety-datasheet.pdf