Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Human |
Format |
Liquid |
Applikationen |
IF |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
BOS-A03622 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
G Protein Signaling, Growth Factors/Hormones, Signal Transduction, Signaling Pathway |
Short Description |
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human. |
Background |
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990). Weinshank R.L., Mol. Pharmacol. 38:681-688(1990). Small K.M., J. Biol. Chem. 276:4917-4922(2001). |
Gene Name |
ADRA2B |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Contents |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application Details |
Immunofluorescence: 1:100~1:500 |
Immunogen |
Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Alpha-2B adrenergic receptor |
Molecular Weight |
49566 MW |
Protein Function |
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.. |
Subcellular Localization |
Cell membrane ; Multi-pass membrane protein. Interaction with RAB26 mediates transport from the Golgi to the cell membrane. |
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