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Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody Europäischer Partner

ArtNr BOS-A03622
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen IF
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Alpha-2B adrenergic receptor;Alpha-2 adrenergic receptor subtype C2;Alpha-2B adrenoreceptor;Alpha-2B adrenoceptor;Alpha-2BAR;ADRA2B;ADRA2L1, ADRA2RL1;
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Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
49566 MW
Clonality
Polyclonal
Application Details
Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name
ADRA2B
Gene Full Name
Alpha-2B adrenergic receptor
Background
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).
Immunogen
Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
G Protein Signaling, Growth Factors/Hormones, Signal Transduction, Signaling Pathway
Protein Function
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Subcellular Localization
Cell membrane; Multi-pass membrane protein. Interaction with RAB26 mediates transport from the Golgi to the cell membrane.
Short Description
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.
Description
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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