Comparison

Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody European Partner

Item no. BOS-A03622
Manufacturer Boster
Amount 100 ul
Category
Type Antibody
Format Liquid
Applications IF
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Alpha-2B adrenergic receptor;Alpha-2 adrenergic receptor subtype C2;Alpha-2B adrenoreceptor;Alpha-2B adrenoceptor;Alpha-2BAR;ADRA2B;ADRA2L1, ADRA2RL1;
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
49566 MW
Clonality
Polyclonal
Application Details
Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name
ADRA2B
Gene Full Name
Alpha-2B adrenergic receptor
Background
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).
Immunogen
Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
G Protein Signaling, Growth Factors/Hormones, Signal Transduction, Signaling Pathway
Protein Function
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Subcellular Localization
Cell membrane; Multi-pass membrane protein. Interaction with RAB26 mediates transport from the Golgi to the cell membrane.
Short Description
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.
Description
Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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