Anti-Peptide YY/PYY Antibody

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

87794 MW

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml

peptide YY

Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a peptide that in humans is encoded by the PYY gene. This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa.
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Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.

Boster Bio Anti-Peptide YY/PYY Antibody Picoband® catalog # A04223-1. Tested in IHC applications. This antibody reacts with Human.

No cross-reactivity with other proteins.