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Anti-EPHB6/Eph Receptor B6 Antibody

Anti-EPHB6/Eph Receptor B6 Antibody

ArtNr	BOS-A04270
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Neuronal Cell Markers Stem Cell Markers
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ephrin type-B receptor 6;HEP;Tyrosine-protein kinase-defective receptor EPH-6;EPHB6;
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	110700 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name	EPHB6
Gene Full Name	Ephrin type-B receptor 6
Background	Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. atsuoka H., Biochem. Biophys. Res. Commun. 235:487-492(1997). Hillier L.W., Nature 424:157-164(2003). Zhang Z., Protein Sci. 13:2819-2824(2004).
Immunogen	Synthesized peptide derived from internal of human EPHB6.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Axonal Guidance Proteins, Cell Type Marker, Growth and Development, Intracellular Signaling, Kinases, Neurology Process, Neuron Marker, Neuroscience, Neurotransmission, Receptors / Channels
Protein Function	Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Short Description	Boster Bio Anti-EPHB6/Eph Receptor B6 Antibody (Catalog # A04270). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-EPHB6/Eph Receptor B6 Antibody (Catalog # A04270). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues.

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BOS-A04270-datasheet.pdf

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