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Anti-Frequenin Ncs1 Antibody Europäischer Partner

ArtNr BOS-A05330
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody
Format Liquid
Applikationen IF
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Dry ice Yes
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FREQUENIN, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog, Frequenin-like protein, NCS 1, NCS1
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Manufacturer - Format
Liquid (sterile filtered)
Clonality
Polyclonal
Application notes
This product was assayed by immunoblot and found to be reactive against Frequenin at a dilution of 1:5000 followed by reaction with Peroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat). Anti-Frequenin is suitable for the detection by immunoblot of human, mouse and rat Frequenin. Anti-Frequenin has also been tested for use in IF using Hippocampal neurons of 17 day old NMRI mice.
Application Details
ELISA: 1:10, 000 - 1:50, 000
IF Microscopy: 1:100-1:2500
WB: 1:500- 1:2, 000
Manufacturer - Gene Name
NCS1
Background
Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
Immunogen
Frequenin (recombinant from Mouse with extensive post-translational modifications)
Contents
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
Purification
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
Concentration
2.0 mg/mL by UV absorbance at 280 nm
Manufacturer - Research Category
Calcium Binding Proteins, Calcium Signaling, Neuroscience, Neurotransmission
Short Description
Boster Bio Anti-Frequenin Ncs1 Antibody (Catalog # A05330). Tested in IF applications. This antibody reacts with Mouse.
Description
Boster Bio Anti-Frequenin Ncs1 Antibody (Catalog # A05330). Tested in IF applications. This antibody reacts with Mouse.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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