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Anti-Frequenin Ncs1 Antibody

Anti-Frequenin Ncs1 Antibody

Item no.	BOS-A05330
Manufacturer	Boster
Amount	100 ug
Category	Neuroscience Neural Signaling Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Format	Liquid
Applications	IF
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Dry ice	Yes
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FREQUENIN, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog, Frequenin-like protein, NCS 1, NCS1
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Manufacturer - Format	Liquid (sterile filtered)
Clonality	Polyclonal
Application notes	This product was assayed by immunoblot and found to be reactive against Frequenin at a dilution of 1:5000 followed by reaction with Peroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat). Anti-Frequenin is suitable for the detection by immunoblot of human, mouse and rat Frequenin. Anti-Frequenin has also been tested for use in IF using Hippocampal neurons of 17 day old NMRI mice.
Application Details	ELISA: 1:10, 000 - 1:50, 000 IF Microscopy: 1:100-1:2500 WB: 1:500- 1:2, 000
Manufacturer - Gene Name	NCS1
Background	Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
Immunogen	Frequenin (recombinant from Mouse with extensive post-translational modifications)
Contents	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
Purification	This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
Concentration	2.0 mg/mL by UV absorbance at 280 nm
Manufacturer - Research Category	Calcium Binding Proteins, Calcium Signaling, Neuroscience, Neurotransmission
Short Description	Boster Bio Anti-Frequenin Ncs1 Antibody (Catalog # A05330). Tested in IF applications. This antibody reacts with Mouse.
Description	Boster Bio Anti-Frequenin Ncs1 Antibody (Catalog # A05330). Tested in IF applications. This antibody reacts with Mouse.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A05330-datasheet.pdf

BOS-A05330-safety-datasheet.pdf