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Anti-SLC9A3R2/Nherf 2 Antibody

Anti-SLC9A3R2/Nherf 2 Antibody

ArtNr	BOS-A05624-1
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies Microglia Markers
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Na (+)/H (+) exchange regulatory cofactor NHE-RF2;NHERF-2;NHE3 kinase A regulatory protein E3KARP;SRY-interacting protein 1;SIP-1;Sodium-hydrogen exchanger regulatory factor 2;Solute carrier family 9 isoform A3 regulatory factor 2;Tyrosine kinase activator protein 1;TKA-1;SLC9A3R2;NHERF2;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	37414 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	SLC9A3R2
Gene Full Name	Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Background	Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. Poulat F., J. Biol. Chem. 272:7167-7172(1997) [PubMed: 9054412]. Reczek D., J. Cell Biol. 139:169-179(1997) [PubMed: 9314537]. Yun C.H.C., Proc. Natl. Acad. Sci. U.S.A. 94:3010-3015(1997) [PubMed: 9096337].
Immunogen	Synthesized peptide derived from internal of human SLC9A3R2.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Microfilaments, Plasma Membrane, Signal Transduction
Protein Function	Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus.
Subcellular Localization	Endomembrane system; Peripheral membrane protein. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern.
Short Description	Boster Bio Anti-SLC9A3R2/Nherf 2 Antibody (Catalog # A05624-1). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-SLC9A3R2/Nherf 2 Antibody (Catalog # A05624-1). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Widely expressed.

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BOS-A05624-1-datasheet.pdf

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