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Anti-GluR4 GRM4 Antibody

Anti-GluR4 GRM4 Antibody

ArtNr	BOS-A06552
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Metabotropic glutamate receptor 4;mGluR4;GRM4;GPRC1D, MGLUR4;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	101868 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name	GRM4
Gene Full Name	Metabotropic glutamate receptor 4
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 - 6313. Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224. Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224. Peyman Golshani, PNAS, Mar 2001; 98: 4172.
Immunogen	Synthesized peptide derived from human GluR4.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Amino Acids, G Protein Signaling, Neuroscience, Neurotransmission, Neurotransmitter, Receptors / Channels, Signal Transduction, Signaling Pathway
Protein Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Short Description	Boster Bio Anti-GluR4 GRM4 Antibody (Catalog # A06552). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-GluR4 GRM4 Antibody (Catalog # A06552). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.

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BOS-A06552-datasheet.pdf

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