Anti-DEDD2 (DED4) Antibody

Rabbit IgG

36179 MW

WB: 1:1000-1:5000

DNA-binding death effector domain-containing protein 2

50 μ l sera

Apoptosis, Cell Biology, Receptors

May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.

Boster Bio Anti-DEDD2 (DED4) Antibody (Catalog# A11263). Tested in WB application(s). This antibody reacts with Canine, Rat, Mouse, Human.

Expressed in most tissues. High levels were found in liver, kidney, heart, ovary, spleen, testes, skeletal muscle and peripheral blood leukocytes. Expression was absent or low in colon and small intestine. Expression is relatively high in the tumor cell lines chronic myologenous leukemia K-562 and the colorectal adenocarcinoma SW480. Expression is moderate in the cervical carcinoma HeLa, the Burkitt's lymphoma Raji, the lung carcinoma A-549, and the melanoma G-361. In contrast, two leukemia cell lines, HL-60 (promyelocytic leukemia) and MOLT-4 (lymphoblastic leukemia), show relatively low levels.