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Anti-TTF-1 NKX2-1 Antibody Europäischer Partner

ArtNr BOS-A30726
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NKX2-1;NKX2A;TITF1;TTF1;Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38596 MW
Clonality
Polyclonal
Application Details
Western Blot, 1:500 - 1:2000
ELISA, 1:10000
Not yet tested in other applications.
Manufacturer - Gene Name
NKX2-1
Gene Full Name
Homeobox protein Nkx-2.1
Immunogen
A peptide derived from human TTF-1. Immunogen sequence location: 27 - 76
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Epigenetics and Nuclear Signaling, Transcription
Protein Function
Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).
Subcellular Localization
Nucleus.
Short Description
Boster Bio Anti-TTF-1 NKX2-1 Antibody (Catalog# A30726). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-TTF-1 NKX2-1 Antibody (Catalog# A30726). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Thyroid and lung.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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