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Anti-RAB7L1 RAB29 Antibody

Anti-RAB7L1 RAB29 Antibody

ArtNr	BOS-A30753
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neuroinflammation Neural Mitochondrial Function Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rab Subfamily
Typ	Antibody
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RAB7L1;Ras-related protein Rab-7L1;Rab-7-like protein 1
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	23155 MW
Clonality	Polyclonal
Application Details	Western Blot, 1:500 - 1:2000 ELISA, 1:20000 Not yet tested in other applications.
Manufacturer - Gene Name	RAB29
Gene Full Name	Ras-related protein Rab-7L1
Immunogen	A peptide derived from human RAB7L1. Immunogen sequence location: 115 - 164
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.
Subcellular Localization	Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847).
Short Description	Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog# A30753). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog# A30753). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitous.

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BOS-A30753-datasheet.pdf

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