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Anti-GPR124 ADGRA2 Antibody

Anti-GPR124 ADGRA2 Antibody

ArtNr	BOS-A30802
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies By Organ Breast Cancer
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Sensitivity	5ul per sample
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GPR124;KIAA1531;TEM5;G-protein coupled receptor 124;Tumor endothelial marker 5
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	142647 MW
Clonality	Polyclonal
Application Details	Western Blot, 1:500 - 1:2000 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications.
Manufacturer - Gene Name	ADGRA2
Gene Full Name	Adhesion G protein-coupled receptor A2
Immunogen	A peptide derived from human GPR124. Immunogen sequence location: 1151 - 1200
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed:16982628).
Subcellular Localization	Cell membrane; Multi- pass membrane protein. Cell projection, filopodium. Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact.
Short Description	Boster Bio Anti-GPR124 ADGRA2 Antibody (Catalog# A30802). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-GPR124 ADGRA2 Antibody (Catalog# A30802). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed in endothelial cells (at protein level) (PubMed:15021905, PubMed:16982628). Abundantly expressed in heart, placenta, ovary, small intestine, and colon (PubMed:15021905).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A30802-datasheet.pdf

BOS-A30802-safety-datasheet.pdf