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Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated Europäischer Partner

ArtNr BOS-FC00910-Biotin
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC
Clon F4-29D9
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Biotin
Sensitivity 5ul per sample
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Complement decay-accelerating factor;CD55;CD55;CR, DAF;
Lieferbar
Manufacturer - Category
Monoclonal Antibodies, Primary Antibodies
Storage Conditions
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
41400 MW
Clonality
Monoclonal
Application Details
User needs to optimize the dilution ratio for this antibody.
Manufacturer - Gene Name
CD55
Gene Full Name
Complement decay-accelerating factor
Background
Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Immunogen
Human umbilical vein endothelial cells
Contents
PBS pH 7.2, 0.09% sodium azide
Purification
Protein A purified
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cell Type Markers, Immunology
Protein Name
Complement decay-accelerating factor
Protein Function
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
Subcellular Localization
Isoform 1: Cell membrane; Single-pass type I membrane protein.
Short Description
Boster Bio Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00910-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Description
Boster Bio Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00910-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Tissue Specificity
Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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