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Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated

Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated

Item no.	BOS-FC00910-Biotin
Manufacturer	Boster
Amount	100 ug
Category	Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	F4-29D9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Biotin
Sensitivity	5ul per sample
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Complement decay-accelerating factor;CD55;CD55;CR, DAF;
Available
Manufacturer - Category	Monoclonal Antibodies, Primary Antibodies
Storage Conditions	Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	41400 MW
Clonality	Monoclonal
Application Details	User needs to optimize the dilution ratio for this antibody.
Manufacturer - Gene Name	CD55
Gene Full Name	Complement decay-accelerating factor
Background	Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Immunogen	Human umbilical vein endothelial cells
Contents	PBS pH 7.2, 0.09% sodium azide
Purification	Protein A purified
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cell Type Markers, Immunology
Protein Name	Complement decay-accelerating factor
Protein Function	This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
Subcellular Localization	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Short Description	Boster Bio Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00910-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Description	Boster Bio Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00910-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Tissue Specificity	Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-FC00910-Biotin-datasheet.pdf

BOS-FC00910-Biotin-safety-datasheet.pdf