Anti-MYD88 Rabbit Monoclonal Antibody, Clone#RM306

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Monoclonal

MYD88

This antibody reacts to human myeloid differentiation primary response protein MyD88

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

Boster Bio Anti-MYD88 Rabbit Monoclonal Antibody, Clone#RM306 (Catalog # M00025-1). Tested in IHC, WB applications. This antibody reacts with Human.

This antibody reacts to human myeloid differentiation primary response protein MyD88