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Anti-Dystrophin DMD Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M00069
Hersteller Boster
Menge 100 ul
Quantity options 100 ul 30 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB
Clon AOGG-4
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10 pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Dystrophin,DMD
Lieferbar
Manufacturer - Category
Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
25 kDa
Calculated Molecular weight
426750 MW
Clonality
Monoclonal
Application Details
WB 1:500-2000
Gene Name
DMD
Gene Full Name
Dystrophin
Immunogen
A synthesized peptide derived from human Dystrophin
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
0.5mg/ml
Manufacturer - Research Category
Biochemicals, Chemical Type, Signal Transduction
Protein Name
P2X purinoceptor 1
Protein Function
Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin- associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Subcellular Localization
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane. In muscle cells, sarcolemma localization requires the presence of ANK2, while localization to costameres requires the presence of ANK3. Localizes to neuromuscular junctions (NMJs) in the presence of ANK2 (By similarity).
Description
Boster Bio Anti-Dystrophin DMD Rabbit Monoclonal Antibody catalog # M00069. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Expressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma. Expressed in brain, muscle, kidney, lung and testis. Isoform 5 is expressed in heart, brain, liver, testis and hepatoma cells. Most tissues contain transcripts of multiple isoforms, however only isoform 5 is detected in heart and liver.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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