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Anti-CDC42 Rabbit Monoclonal Antibody

Anti-CDC42 Rabbit Monoclonal Antibody

ArtNr	BOS-M00119
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Antibodies Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies small GTPases Rho Subfamily
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IP, IHC
Clon	IAE-3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<12 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cell division control protein 42 homolog,G25K GTP-binding protein,CDC42
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	70 kDa
Calculated Molecular weight	21259 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 IP 1:30 FC 1:50
Gene Name	CDC42
Gene Full Name	Cell division control protein 42 homolog
Immunogen	A synthesized peptide derived from human CDC42
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Cancer, Cell Biology, Cell Cycle, Cell Division, Cytokinesis, Epigenetics and Nuclear Signaling, G Protein Signaling, Kinases/Phosphatases, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport
Protein Name	P2X purinoceptor 1
Protein Function	Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
Subcellular Localization	Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase. Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells. Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1. Colocalizes with NEK6 in the centrosome.
Description	Boster Bio Anti-CDC42 Rabbit Monoclonal Antibody catalog # M00119. Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00119-datasheet.pdf

BOS-M00119-safety-datasheet.pdf