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Anti-p21 CDKN1A Rabbit Monoclonal Antibody

Anti-p21 CDKN1A Rabbit Monoclonal Antibody

ArtNr	BOS-M00145-3
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Senescence Primary Antibodies By Organ Lung Cancer Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, IHC, ICC
Clon	ACG-3
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<50 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclin-dependent kinase inhibitor 1,CDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21,CDKN1A,CAP20,CDKN1,CIP1,MDA6,PIC1,SDI1,WAF1
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Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	95 kDa
Calculated Molecular weight	18119 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:50
Gene Name	CDKN1A
Gene Full Name	Cyclin-dependent kinase inhibitor 1
Immunogen	A synthesized peptide derived from human p21
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Chromatin Binding Proteins, Co-Activators/Co-Repressors, DNA/RNA Binding, Domain Families, Epigenetics and Nuclear Signaling, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Transcription, Zinc Finger
Protein Name	P2X purinoceptor 1
Protein Function	May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Subcellular Localization	Cytoplasm. Nucleus.
Description	Boster Bio Anti-p21 CDKN1A Rabbit Monoclonal Antibody catalog # M00145-3. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Tissue Specificity	Expressed in all adult tissues, with 5-fold lower levels observed in the brain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M00145-3-datasheet.pdf

BOS-M00145-3-safety-datasheet.pdf