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Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody

Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody

ArtNr	BOS-M00179
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Lipid & Fatty Acid Transport Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC, ICC
Clon	GE-3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<50 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Caveolin-1,CAV1,CAV
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	70 kDa
Calculated Molecular weight	20472 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 FC 1:20
Gene Name	CAV1
Gene Full Name	Caveolin-1
Immunogen	A synthesized peptide derived from human Caveolin-1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Calcium Channels, Calcium Signaling, Cancer, Cancer Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmission, Pathways and Processes, Signal Transduction, Signaling Pathway
Protein Name	P2X purinoceptor 1
Protein Function	May act as a scaffolding protein within caveolar membranes. Interacts ly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Subcellular Localization	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae.
Description	Boster Bio Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody catalog # M00179. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in muscle and lung, less so in liver, brain and kidney.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00179-datasheet.pdf

BOS-M00179-safety-datasheet.pdf