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Anti-TLR9 Rabbit Monoclonal Antibody

Anti-TLR9 Rabbit Monoclonal Antibody

ArtNr	BOS-M00198
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Neuroinflammation Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	ABFH-20
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<50pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Toll-like receptor 9;CD289;TLR9;UNQ5798/PRO19605;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	103 kDa
Calculated Molecular weight	115860 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000
Manufacturer - Gene Name	TLR9
Gene Full Name	Toll-like receptor 9
Immunogen	A synthesized peptide derived from human TLR9
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adapters, Immunoglobulins, Immunology, Innate Immunity, Macrophage/Inflammation, Receptors, Signal Transduction, TLR Signaling, Transmembrane
Protein Name	P2X purinoceptor 1
Protein Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
Subcellular Localization	Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Description	Boster Bio Anti-TLR9 Rabbit Monoclonal Antibody catalog # M00198. Tested in WB application. This antibody reacts with Human.
Tissue Specificity	Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00198-datasheet.pdf

BOS-M00198-safety-datasheet.pdf