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Anti-GSK3 beta Rabbit Monoclonal Antibody

Anti-GSK3 beta Rabbit Monoclonal Antibody

ArtNr	BOS-M00791
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Metabolism Diabetes Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Progenitor Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC, ICC
Clon	EB-7
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glycogen synthase kinase-3 beta;GSK-3 beta;2.7.11.26;Xgsk-3 protein;gsk3b;Xgsk-3;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	52 kDa
Calculated Molecular weight	46903 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:3000 IHC 1:50-1:200 ICC/IF 1:100-1:500 FC 1:200-1:500
Manufacturer - Gene Name	GSK3B
Gene Full Name	Glycogen synthase kinase-3 beta
Immunogen	A synthesized peptide derived from human GSK3 beta
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Carbohydrate Metabolism, Cell Biology, Cell Cycle, Cell Differentiation, Developmental Biology, Energy Metabolism, Metabolic Signaling Pathways, Metabolism, Nervous System Development, Neurogenesis, Neurology Process, Neuroscience, Organogenesis, Pathways and Processes, Signal Transduction
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Plays a role in the organization of the formation of the main body axis of developing embryo. Acts as an inhibitor of differentiation of primary neurons. Inhibits the ability of ectopically expressed NEUROD1 and other bHLH factors to promote early retinal cell differentiation. May participate in the Wnt signaling pathway. May regulate the circadian clock via phosphorylation of the major clock components.
Subcellular Localization	Cytoplasm. Nucleus. Cell membrane.
Description	Boster Bio Anti-GSK3 beta Rabbit Monoclonal Antibody catalog # M00791. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00791-datasheet.pdf

BOS-M00791-safety-datasheet.pdf