« Zurück
Startseite /
Anti-APAF1 Rabbit Monoclonal Antibody

Anti-APAF1 Rabbit Monoclonal Antibody

ArtNr	BOS-M00889
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC
Clon	BHF-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Apoptotic protease-activating factor 1,APAF-1,APAF1,KIAA0413
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	52 kDa
Calculated Molecular weight	141840 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200
Gene Name	APAF1
Gene Full Name	Apoptotic protease-activating factor 1
Immunogen	A synthesized peptide derived from human APAF1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Apoptosis, Apoptotic Markers, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Subcellular Localization	Cytoplasm.
Description	Boster Bio Anti-APAF1 Rabbit Monoclonal Antibody catalog # M00889. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00889-datasheet.pdf

BOS-M00889-safety-datasheet.pdf