Anti-S100-beta Rabbit Monoclonal Antibody, Clone#RM304

Rabbit IgG

10713 MW

Immunohistochemistry (IHC): 1:500-1:1000 dilution

WB: 1:100-1:200 dilution.

Protein S100-B

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Boster Bio Anti-S100-beta Rabbit Monoclonal Antibody, Clone#RM304 (Catalog # M00979-2). Tested in IHC, WB applications. This antibody reacts with Human.

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.