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Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2) Europäischer Partner

ArtNr BOS-M01014
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IP
Clon Vicky-2
Specific against Mouse (Murine, Mus musculus)
Host Rat
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 17;B-cell maturation protein;CD269;Tnfrsf17;Bcm, Bcma;
Lieferbar
Manufacturer - Category
Primary Antibodies, Monoclonal Antibodies
Observed Molecular Weight
20442 MW
Clonality
Monoclonal
Application Details
WB, 1:1, 000, Mouse
IP, 1:200, Mouse
Manufacturer - Gene Name
Tnfrsf17
Gene Full Name
Tumor necrosis factor receptor superfamily member 17
Background
TNFRSF17 (Tumor necrosis factor receptor superfamily member 17), also called BCMA, is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily and is mapped to 16p13.13. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Immunogen
Recombinant mouse BCMA extracellular domain (aa 1-46).
Contents
Each vial contains 0.02% sodium azide.
Purification
Protein G-affinity purified.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Antiviral Signaling, Cancer, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Signal Transduction
Protein Name
Tumor necrosis factor receptor superfamily member 17 (Tnfrsf17)
Protein Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (By similarity).
Subcellular Localization
Membrane; Single-pass type III membrane protein.
Short Description
Boster Bio Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2) catalog # M01014. Tested in IP, WB applications. This antibody reacts with Mouse.
Description
Boster Bio Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2) catalog # M01014. Tested in IP, WB applications. This antibody reacts with Mouse.
Tissue Specificity
Detected in spleen, thymus, bone marrow and heart, and at lower levels in kidney and lung.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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