« Back
Home /
Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2)

Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2)

Item no.	BOS-M01014
Manufacturer	Boster
Amount	100 ug
Category	Oncology Metabolism Diabetes Antibodies By Cell Type Hematology Myeloma Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP
Clone	Vicky-2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 17;B-cell maturation protein;CD269;Tnfrsf17;Bcm, Bcma;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies
Observed Molecular Weight	20442 MW
Clonality	Monoclonal
Application Details	WB, 1:1, 000, Mouse IP, 1:200, Mouse
Manufacturer - Gene Name	Tnfrsf17
Gene Full Name	Tumor necrosis factor receptor superfamily member 17
Background	TNFRSF17 (Tumor necrosis factor receptor superfamily member 17), also called BCMA, is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily and is mapped to 16p13.13. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Immunogen	Recombinant mouse BCMA extracellular domain (aa 1-46).
Contents	Each vial contains 0.02% sodium azide.
Purification	Protein G-affinity purified.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Antiviral Signaling, Cancer, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Signal Transduction
Protein Name	Tumor necrosis factor receptor superfamily member 17 (Tnfrsf17)
Protein Function	Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (By similarity).
Subcellular Localization	Membrane; Single-pass type III membrane protein.
Short Description	Boster Bio Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2) catalog # M01014. Tested in IP, WB applications. This antibody reacts with Mouse.
Description	Boster Bio Anti-BCMA Tnfrsf17 Antibody (Monoclonal, Vicky-2) catalog # M01014. Tested in IP, WB applications. This antibody reacts with Mouse.
Tissue Specificity	Detected in spleen, thymus, bone marrow and heart, and at lower levels in kidney and lung.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01014-datasheet.pdf

BOS-M01014-safety-datasheet.pdf