Anti-Cytokeratin 8 KRT8 Antibody Picoband® (monoclonal, 3G9)

Mouse IgG2b

54 kDa

Western blot, 0.1-0.5?g/ml

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml

Immunohistochemistry (Frozen Section), 0.5-1?g/ml

Immunofluorescence, 2?g/ml

Immunocytochemistry/Immunofluorescence, 2?g/ml

Flow Cytometry (Fixed), 1-3?g/1x10⁶ cells

keratin 8

Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Keratin, Signal Transduction

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Boster Bio Anti-Cytokeratin 8 KRT8 Antibody Picoband® (monoclonal, 3G9) catalog # M01421-3. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.