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Anti-67kDa Laminin Receptor RPSA Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M01691
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IF, IP, IHC, ICC
Clon AOAO-18
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias 40S ribosomal protein SA ;37 kDa laminin receptor precursor ;37LRP ;37/67 kDa laminin receptor ;LRP/LR ;67 kDa laminin receptor ;67LR ;Colon carcinoma laminin-binding protein;Laminin receptor 1 ;LamR ;Laminin-binding protein precursor p40 ;LBP/p40 ;Multidrug resistance-associated protein MGr1-Ag;NEM/1CHD4;RPSA ;LAMBR, LAMR1;
Lieferbar
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular weight
32854 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50
Manufacturer - Gene Name
RPSA
Gene Full Name
40S ribosomal protein SA
Immunogen
A synthesized peptide derived from human 67kDa Laminin Receptor
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cancer, Cancer Metabolism, Endocrine Metabolism, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolism, More Gpcr, Neurology Process, Neuropeptides, Neuroscience, Neurotransmission, Neurotransmitter, Pathways and Processes, Receptors / Channels
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA.
Subcellular Localization
Cell membrane. Cytoplasm. Nucleus. 67LR is found at the surface of the plasma membrane, with its C-terminal laminin- binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity). Colocalizes with PPP1R16B in the cell membrane.
Description
Boster Bio Anti-67kDa Laminin Receptor RPSA Rabbit Monoclonal Antibody catalog # M01691. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Expressed in both pancreatic alpha- and beta- cells (at protein level). Expressed at higher levels in the pancreas than other somatostatin receptors. Also expressed in the cerebrum and kidney and, in lesser amounts, in the jejunum, colon and liver. In the developing nervous system, expressed in the cortex where it is located in the preplate at early stages and is enriched in the outer part of the germinal zone at later stages. In the cerebellum, expressed in the deep part of the external granular layer at gestational week 19. This pattern persists until birth but disappears at adulthood.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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