Anti-HTRA2/Omi Rabbit Monoclonal Antibody

ArtNr	BOS-M01941
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Allergenes Neuroscience Neuroinflammation Neural Mitochondrial Function Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IP, IHC
Clon	EEH-8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Serine protease HTRA2, mitochondrial;3.4.21.108;High temperature requirement protein A2;HtrA2;Omi stress-regulated endoprotease;Serine protease 25;Serine proteinase OMI;HTRA2;OMI, PRSS25;
Lieferbar
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	28 kDa
Calculated Molecular weight	48841 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 IP 1:30
Manufacturer - Gene Name	HTRA2
Gene Full Name	Serine protease HTRA2, mitochondrial
Immunogen	A synthesized peptide derived from human HTRA2
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Apoptosis, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism
Protein Name	Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Subcellular Localization	Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
Description	Boster Bio Anti-HTRA2/Omi Rabbit Monoclonal Antibody catalog # M01941. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform 1 is ubiquitous. Isoform 2 is expressed predominantly in the kidney, colon and thyroid.

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Arbeitsanleitung (Data Sheet) anfordern

BOS-M01941-datasheet.pdf

BOS-M01941-safety-datasheet.pdf