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Anti-Caspase-10 Rabbit Monoclonal Antibody

Anti-Caspase-10 Rabbit Monoclonal Antibody

ArtNr	BOS-M02190-1
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IP, IHC
Clon	ICH-3
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Caspase-10;CASP-10;3.4.22.63;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4;Caspase-10 subunit p23/17;Caspase-10 subunit p12;CASP10;MCH4;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	27 kDa
Calculated Molecular weight	58951 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:100 IP 1:50 FC 1:50
Manufacturer - Gene Name	CASP10
Gene Full Name	Caspase-10
Immunogen	A synthesized peptide derived from human Caspase-10
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes
Protein Name	Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-\|-AMC and Asp-Glu-Val-Asp-\|-AMC.
Subcellular Localization	Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit. Cell projection, pseudopodium. Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity).
Description	Boster Bio Anti-Caspase-10 Rabbit Monoclonal Antibody catalog # M02190-1. Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human.
Tissue Specificity	Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M02190-1-datasheet.pdf

BOS-M02190-1-safety-datasheet.pdf